Endocrine Abstracts

The use insulin pump therapy (IPT) (continuous subcutaneous insulin infusion (CSII)) has increased dramatically in youth with type 1 diabetes (T1D) in the past decade.Objective: Rate metabolic compensation of diabetes mellitus in children on IPT on the level HbA1c and self-control of glycaemia.Methods: The examination of 19 children aged 12.55±3.75 years (boys/girls=13/6), with T1D, observed in ‘2nd City Children’s H...

Hypothalamic amenorrhoea is a diagnosis of exclusion, frequent cause of which are medications or psychiatric disorders (bulimia/anorexia). Here we present a case, when its aetiology was gender identity disorder. A 18-year-old girl presented with absence of menses during last year. Menses began at the age of 14 and were regular till age of 16, when she moved to another city. She was seen by gynaecologist because of amenorrhea, and evaluation was performed: FSH 4.6 mU/ml (1.37&#...

Objective: To study feeding habits in children of different ages with alimentary obesity compared with normative values.Methods: We compared 3 days food diaries of 98 children with alimentary obesity observed in the Endocrinology Department of University Hospital (Minsk) with nutritional standards of healthy children recommended by Belarusian National Center for Hygiene, Epidemiology and Public Health – control (K). Patients were divided into three ...

The aim: To evaluate the efficiency and safety of using closed loop systems in patients with type 1 DM living in Russia.Results: 88 respondents (or those legal representatives) with type 1 DM in insulin therapy by closed loop systems, members of Russian-speaking community, were included to the study. 90% of respondents living in Russia. All respondents using do-it-yourself artificial pancreas systems (DIYAPS): Loop (19.3%), Open APS (30.7%) and Andr...

Background: The function of the thyroid gland effects on obesity and comorbidities. It has been proven for bariatric surgery to be the most effective in obesity treatment.Aim: To evaluate the dynamics of body weight, thyroid status, leptin and insulin resistance in obese patients after bariatric surgery.Materials and methods: 78 obese patients were observed after bariatric surgery (sleeve gastrectomy – 46, gastric bypass &#82...

Introduction: Graves’ disease (GD) is an autoimmune disorder of the thyroid gland, which is characterisied by a breakdown in immune tolerance. The lymphocytic infiltration of the thyroid leads to production of autioantibodies targeting thyroid stimulating hormone receptor (TSHR). The clinical course of GD varies among patients and it is difficult to predict the relapse risk after antithyroid therapy withdrawal. It is believed that GD occurs due to genetic suspectibility ...

Introduction: Radioiodine is used for the treatment of Thyrotoxicosis when medical treatment (anti-thyroid drugs) has failed or cannot be tolerated and surgical treatment is not an option. We aimed to assess our compliance with the Royal College of Physicians (RCP) guidelines for Radioiodine treatment, and assess patient satisfaction with our Radioiodine service.Methods: Notes for patients who received Radioiodine treatment between January 2010 and April...

Thyroid disease is associated with atherosclerosis cardiovascular disease. This is undoubted for overt hypothyroidism, but is controversy in subclinical hypothyroidism hittle is known about the relationship between insulin resistance and thyroid function. It is well known that insulin resistance is the main part of metabolic syndrome. We aimed to investigate the relationship between thyroid function, body mass index (BMI) and homeostasis model assessment index for insulin resi...

Subclinical hypothyroidism (SH) is very frequent condition in older population. If can occur in 12–20% of patients older than 60. It is well known today that thyroid hormones can increase gene expression of APO-B receptors in the liver and by this way improve catabolism of atherogenic lipoproteins. They also can regulate processes of contractility and weakening of heart muscle. Decrease of cardiac output and diastolic disfunction of left ventricle can be revealed in SH pa...

Adrenal incidentaloma (AI) in patients with cancer poses diagnostic challenge for doctors. We present clinical case of generalised metastatic bone diseases and adrenal mass.Male 59 years old asked the second opinion about incidental adrenal mass, which was suspected for adrenal cancer by urologist. His medical anamnesis began in April of 2015 with severe generalised bone pain. The whole body MRI/CT detected multiple bone lesions, adrenal mass (57×45...